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Ta sk f o rce m em bersa re a ssigned a cco rding to theirrespective have been a ssigned a cco rding to a m o dif ed versio n o the Na tio na lC o m prehensive C a ncerNetwo rk a rea so expertise a nd clinica linteresta nd m em bership isupda ted each 2 yea rs listo f C a tego rieso C o nsensus, a s o llo ws these ta sk f o rcesa nd theirm em bership isincluded in the C o ntributo rs sectio n o f this C ateg ory tatem entof C onsensu s do cum ent, ref ecting co ntributio nsa nd reco m m enda tio nsreleva ntto the currentrelea se o these tips Versio n 5 O cto ber There isunio rm co nsensuso the pa neltha t 1 There ishigh- levelevidence linking the la the ef ectwith the thera peutic A llrevisio nspro po sed by the ta sk f o rceswere eva lua ted by a pa nelo f experts, a nd i expo sure a ccepted, a ssigned a sco re (see Sco ring Expla na tio n sectio n o f Pref a ce). 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Hemorrhage andHemorrhage and Cellular and MatrixCellular and Matrix RemodelingRemodeling InflammationInflammation ProliferationProliferation TendinopathyTendinopathy andand tendon’s responsetendon’s response toto injuryinjury TendinopathyTendinopathy andand tendon’s responsetendon’s response toto injuryinjury Factors that may adversely affect the healingFactors which will adversely affect the therapeutic Factors that may adversely affect the healingFactors which will adversely have an effect on the therapeutic response of tendons to an overresponse of tendons to an over-use injury:use injury: response of tendons to an over-response of tendons to an over-use damage:use harm: •• Tissue: tendons have an inherently slow metabolicTissue: tendons have an inherently gradual metabolic • Tissue: tendons have an inherently sluggish metabolic• Tissue: tendons have an inherently sluggish metabolic price and a limited cell inhabitants. 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